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The Science Behind ElevatedCPR™ Therapy

Pre-clinical scientific data has demonstrated that precise multi-angled patient positioning along with a timed elevation sequence dramatically enhances the potential outcomes of device-assisted head up CPR, or ElevatedCPR therapy.1,2 The positioning of the patient, the speed at which the patient is elevated into the ElevatedCPR position after initial supine CPR priming, and the height to which the head is elevated over the heart and the heart over the lower part of the body are all critical components to produce the optimal physiological response to ElevatedCPR.

The results of ElevatedCPR therapy are optimized when used with a bundle of care including active compression-decompression and/or mechanical CPR devices and an impedance threshold device (ITD) to help regulate the intrathoracic pressure while CPR is being performed.3,4,5,6

Pre-clinical studies exploring ElevatedCPR therapy as part of a bundle of care have shown a strong potential to improve resuscitation and survival from sudden cardiac arrest.5,6,7 Pre-clinical studies of ElevatedCPR therapy have shown doubled blood flow to and through the brain and other vital organs compared to today’s best-of-class CPR techniques and devices.6 In addition, when compared to circulation from hands-only CPR with the patient supine or head flat, the increase in cerebral circulation is profound, nearly 4-fold after 15 minutes of CPR.9 ElevatedCPR therapy also produces an immediate and significant reduction in intracranial pressure.6

Human cadaver studies with active compression decompression CPR with an ITD and with an automated CPR device with an ITD show physiologic results consistent with the pre-clinical studies.9