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Lisa Owens
LisaOwens@ElevatedCPR.com
210-601-6647

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[November 18, 2019 Minneapolis, MN] Two posters presented this weekend at the American Heart Association’s Resuscitation Science Symposium demonstrate the benefits of device assisted head up CPR using controlled sequential elevation, which is a hallmark of AdvancedCPR Solutions’ ElevatedCPR® Method.
  • Controlled Sequential Elevation of the Head and Thorax Rapidly Achieves 50% of Baseline Cerebral Perfusion Pressure During Active Compression-Decompression Cardiopulmonary Resuscitation With an Impedance Threshold Device in a Swine Model of Cardiac Arrest, by Carolina Rojas-Salvador, was presented on November 16. The animal study set out to determine the optimal controlled sequence of elevation (CSE) to achieve a 50 percent baseline Cerebral Perfusion Pressure (CerPP) with active compression-decompression CPR and an impedance threshold device. The study compared a 4-minute elevation sequence to 10-minute elevation sequence, all with 2 minutes of “priming” prior to initiating elevation. Based on the results of the initial test, additional animals were studied with an elevation sequence of two minutes preceded by two minutes of priming, and a fourth group with a 24 second elevation and no priming. The presenter concluded “A 50% BL CerPP value was achieved in <3 minutes by combining a priming step and 2-min CSE time together with ACD+ITD CPR. This optimized approach is more advantageous than the 24-sec or 10-min elevation.”
  • Controlled Sequential Elevation of the Head and Thorax Combined With Active Compression Decompression Cardiopulmonary Resuscitation and an Impedance Threshold Device Improves Neurological Survival in a Swine Model of Cardiac Arrest, by Johanna C. Moore, was presented on November 17. The study hypothesized that active compression-decompression CPR (ACD-CPR) and an impedance threshold device (ITD) with controlled sequential elevation of the head and thorax (CSE) could increase neurologically intact survival when compared to conventional (C) CPR in the flat position. The study compared survival (measured by return of spontaneous circulation) and neurologically-intact outcomes (measured by a CPC score of 1-2) in animals receiving standard flat CPR and CPR using a controlled elevation sequence of two minutes of priming in the lowest position and a two minute elevation combined with ACD-CPR and an ITD. Eight of eight (100%) animals who received controlled sequential elevation with ACD-CPR and ITD achieved ROSC and six of eight (75%) were determined to be neurologically intact. In the standard CPR group, only two of eight (25%) animals achieved ROSC and only one of eight (12.5%) was determined to be neurologically intact. The presenter concluded that “The novel bundled resuscitation approach of CSE with ACD+ITD CPR increased neurologically intact survival 6-fold versus C-CPR in a swine model of cardiac arrest.”
AdvancedCPR Solutions’ ElevatedCPR method is a broad, patent-protected and technologically-advanced technique for performing device-assisted head up CPR that incorporates raising the head, heart, and thorax in a multi-level elevation, in a timed sequence, in conjunction with the best practice standards of resuscitation protocols. Preclinical studies have demonstrated a number of benefits associated with the ElevatedCPR method relative to intracranial pressure (ICP),1 2 3 cerebral perfusion pressure (CerPP)1 2 3 4 5 6 7 and coronary perfusion pressure (CorPP).2 3 4 5 6 7The company’s initial device, the EleGARDTM Patient Positioning System, is intended to assist in controlled elevation of the head and thorax of a patient from a supine position into a multi-level elevated position with the head above the thorax and the thorax above the lower body and extremities, and may be used for airway management procedures and CPR. It is the only device that precisely, rapidly, and consistently positions patients in a multi-level elevation to support the practice of the ElevatedCPR method in the pre-hospital and hospital settings.Founded in Minneapolis, Minnesota in 2015 by an experienced team that previously developed multiple novel resuscitation technologies currently in widespread clinical practice, AdvancedCPR Solutions is an early stage medical device firm focused on the development and commercialization of delivery mechanisms, methods and devices that enable the ElevatedCPR method to potentially improve survival of cardiac arrest.  The company’s first device, the EleGARD Patient Positioning System, was launched for use in the US earlier this year.###1 Debaty, Resuscitation 2015; 2 Ryu, Resuscitation 2016; 3 Moore, Resuscitation 2018; 4 Kim, Resuscitation, 2017; 5 Moore, Circulation 2018; 6 Rojas, NAEMSP 2019; 7 Frascone, Gathering of Eagles 2019

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[August 29, 2019: Minneapolis, MN] Sixty-year old Greg Eubanks doesn’t remember much about that day in the Minneapolis-St. Paul International Airport.  He was walking from one gate to the next when he collapsed without warning, suffering a sudden cardiac arrest.  Bystanders saw Greg, a physically-fit succulent plant landscaper from California, collapse and alerted TSA airport officials, who quickly started to perform CPR.The statistical odds for patients like Greg surviving sudden cardiac arrest are grim: in the US, there are about 350,000 out of hospital cardiac arrests each year, and the survival rate is 10 percent. Furthermore, Greg had suffered a type of cardiac arrest called refractory ventricular fibrillation (RVF), a complicated cardiac arrhythmia that does not typically respond to conventional CPR and multiple AED shocks.  Generally, these patients have a completely blocked main artery in the heart, and they usually do not survive.The first responders administered shocks from a nearby automated external defibrillator device (AED) but Greg remained in cardiac arrest until airport fire rescue arrived and deployed their bundle of cardiac arrest care, including the latest technology in their arsenal – an EleGARD™ Patent Positioning Device.   Allina incorporated the EleGARD System into its bundle of care in May of this year.“We recently added device-assisted head up CPR with the EleGARD System to our bundle of care for cardiac arrest, and clearly it’s making a difference” commented Charlie Lick, MD, an Emergency Medicine Physician and Medical Director for Allina Medical Transportation in charge of airport CPR protocols.Once resuscitated after eight defibrillator shocks and multiple doses of adrenaline, Greg was transported to Abbott Northwestern Hospital where he was taken to the heart catheterization lab. He was found to have 100 percent blockage of his artery which was opened with a stent in an effort to save his life.Against the odds, and thanks to the newest technologies deployed by the paramedics and other EMS personnel at the Minneapolis Airport, Greg walked out of the hospital less than a week after his cardiac arrest and returned home to his family in full health.Greg and his family recently reunited with the TSA agents who responded to his cardiac arrest, and he is looking forward to meeting the paramedics who treated him from Allina.  “Thanks to the first responders who treated me, and to Allina’s adoption of the EleGARD System, I have a renewed lease on life. Every moment spent with my family now is a credit to the TSA personnel who started CPR, the airport paramedics, and the bundled approach with head up CPR that Dr. Lick introduced to improve outcomes after cardiac arrest.   I am fortunate that I suffered my event when and where I did, because Minneapolis-St. Paul is the only airport in the world so far to use the EleGARD System. Every airport should adopt this approach to save patients like me.”Dr. Keith Lurie, who helped invent the EleGARD System and is a world-renown expert on resuscitative science, commented, “Bystander CPR is critical to start the resuscitation process but it is usually not, by itself, sufficient. The scientific advances we are making in the laboratory have resulted in new tools to improve survival of cardiac arrest in the field, and they are having a measurable impact.  We now more fully understand the physiology of CPR and how to substantially improve its practice. This requires a whole new approach to resuscitation embodied in the ElevatedCPR method.  We do this because cardiac arrest should be a survivable event, with the knowledge and strides forward we have made in the last decade. To talk with Greg and see the results in this one patient means the world to me.”Founded in Minneapolis, Minnesota in 2015 by an experienced team that previously developed multiple novel resuscitation technologies currently in widespread clinical practice, AdvancedCPR Solutions is an early stage medical device firm focused on the development and commercialization of delivery mechanisms, methods and devices that enable the ElevatedCPR method to potentially improve survival of cardiac arrest.  The company’s first device, the EleGARD Patient Positioning System, was launched for use in the US earlier this year. 

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[July 30, 2019: Minneapolis, MN] AdvancedCPR Solutions has completed the requirements to apply the CE Mark for its EleGARD Patient Positioning System.  The CE marking confirms that the EleGARD System meets the requirements of the European Medical

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[July 24, 2019: Minneapolis, MN] The U.S. Patent and Trademark Office (USPTO) has issued emerging medical device firm AdvancedCPR Solutions its fourth patent related to its ElevatedCPR method. The patent (U.S. Patent No. 10,350,137) is exclusively

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[June 4, 2019: Minneapolis, MN] AdvancedCPR Solutions has engaged Illinois-based medical device distributor MED Alliance International, LLC, to handle the logistical and fulfillment needs for the EleGARD™ Patient Positioning System, a device

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[April 18, 2019: Minneapolis, MN] The U.S. Patent and Trademark Office (USPTO) has issued emerging medical device firm AdvancedCPR Solutions (formerly Minnesota Resuscitation Solutions) an additional broad method patent for its ElevatedCPR method,

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