[June 5, 2020: Minneapolis, MN]  The U.S. Patent and Trademark Office (USPTO) has issued emerging medical device firm AdvancedCPR Solutions its ninth patent related to the company’s ElevatedCPR™ method. The broad method patent (U.S. Patent No. 10,667,987) is exclusively licensed to the company and covers methods for performing CPR with a patient in a supine position for a period of time, followed by CPR with the patient’s head and/or torso elevated, and with forceful chest compressions that are uniformly distributed across the compression surface during each chest compression.

“Our preclinical studies have demonstrated that the combination of controlled multi-level elevation along with a timed sequence of events significantly enhances the outcomes of the ElevatedCPR method,” commented Philip Faris, AdvancedCPR Solutions’ CEO.  “This patent further protects the intellectual property we are developing from evidence-based research.”

AdvancedCPR Solutions’ ElevatedCPR method could potentially improve outcomes from cardiac arrest, one of the leading causes of death worldwide, by lifting the head, heart, and thorax in a multi-level elevation, in a timed sequence, in conjunction with a bundle of care that includes the best practice standards of resuscitation protocols. ¹ This positioning allows the body to drain venous blood from the brain while CPR is being performed; and preclinical evidence shows a number of potential benefits associated with this method relative to intracranial pressure (ICP), cerebral perfusion pressure (CerPP) and coronary perfusion pressure (CorPP).^{2 3 4 5}

Preclinical studies have demonstrated that a timing and elevation sequence that includes a two minute period of high quality CPR with active compression-decompression CPR or mechanical CPR and an impedance threshold device with the patient in the lowest elevation, followed by a slow progressive rise over two minutes to the highest elevation, significantly increases cerebral perfusion pressure to greater than 80 percent of normal and coronary perfusion pressure to greater than 70 percent of normal.^{. 2 3 6 7 8}

The company’s initial device, the EleGARD^TM Patient Positioning System, is the only device that precisely and consistently positions the patient in a multi-level elevation to support the practice of the ElevatedCPR method⁹ in the pre-hospital and hospital settings. An initial study investigating its use with a state-of-the-art bundle of care has shown significant improvements in return of spontaneous circulation (ROSC) ⁹ which is a strong indicator of potential survival from cardiac arrest.

Founded in Minneapolis, Minnesota in 2015 by an experienced team that previously developed multiple novel resuscitation technologies currently in widespread clinical practice, AdvancedCPR Solutions is focused on the development and commercialization of delivery mechanisms, methods and devices that enable the ElevatedCPR method.

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1 Strobos, Resuscitation 2018
2 Moore, et al., Circulation 2018
3 Rojas, et al., NAEMSP 2019 (Fig. 4)
4 Moore, et al., Resuscitation 2017
5 Moore, et al., Resuscitation 2018
6 Frascone, Gathering of Eagles 2019
7 Rojas, et al., Resuscitation 2020
8 Moore, et al., Resuscitation 2020
9 Scheppke, Prehospital Emergency Care 2020

The EleGARD™ Patient Positioning System is intended to assist in elevating the head and the thorax of a patient from a supine position into a multi-level elevated position with the head above the thorax and the thorax above the lower body and extremities, and may be used during various procedures, i.e., airway management, CPR, etc.